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It induces apoptosis in malignant cells by upregulating p27kip1 and Caspase-3, acting as a "smart" molecule that supports healthy cells while targeting damaged ones

The puromycin resistance gene and BFP of the pKLV2-U6gRNA5(BbsI)-PGKpuro2ABFP-W (a gift from Kosuke Yusa, Addgene plasmid #67974) 82 were replaced by IRES-HygR and EGFP, as vector backbone

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Retrieved September 9, 2021

Texture: Gummy