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GIP receptor activation enhances insulin secretion, modulates adipose tissue metabolism, and appears to synergise with GLP-1 activity to produce greater metabolic effects than either hormone alone as demonstrated by the clinical performance of the dual agonist tirzepatide

Acta Diabetol (1995) 32(1):136

Other Weight Management Medications in Obese and Overweight Patients

Maintenance Dose Strategy Many researchers and clinicians are exploring reduced maintenance dosing as a middle ground between full-dose treatment and complete discontinuation

People who have very little weight loss may still get real benefit for treating cardiovascular and liver disease, sleep apnea, and a range of inflammatory and neurological diseases

This is particularly relevant for medications with narrow therapeutic windows like blood thinners, seizure medications, and certain antibiotics