By bolstering fatty acid transport into the mitochondria, L-carnitine may help mitigate fat storage and promote the utilization of dietary fats for energy
In previous study, L-theanine and its derivatives, ethyl 6-bromocoumarin-3-carboxylyl L-theanine (TBrC), could effectively prevent the growth and migration of highly metastatic human cervical cancer cells, which was confirmed by in vitro and in vivo studies (69)
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Peptide-functionalized LNPs, guided by exenatide-derived ligands, have additionally achieved targeted mRNA delivery across the blood-brain barrier, establishing a framework for neuroendocrine applications of GLP-1R-targeted gene therapy [116, 427]
Sample sizes were generally small, with 10 out 11 studies including fewer than 20 participants per group