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Incretin hormones: Their role in health and disease

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The gut is not only responsible for digestion but also plays a significant role in hormone production, appetite regulation, and overall well-being.When functioning properly, it sends clear messages to the brain that help control hunger, regulate blood sugar levels, and maintain steady energy levels.When disrupted by stress, poor diet, or lack of sleep, those signals become less reliable - leading to cravings, overeating, and weight gain

If You Have Pre-Existing Thyroid Conditions If you have hypothyroidism and take levothyroxine, your provider may recommend checking TSH and free T4 levels more frequently during the first few months of GLP-1 therapy and after significant weight loss

Most patients manage it easily by staying hydrated, eating smaller portions, and not pushing past fullness

This early satiety effect is a therapeutic benefit of the medication's action on appetite centres in the brain and gastric emptying