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As such, it should be administered by trained professionals after a thorough assessment of the patient

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Hofbauer KG, Nicholson JR, Boss O

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It is recommended to conduct an allergy test 24-48 hours before the procedure

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Options include: Changing from one oral tablet formulation to another with different excipients Discussing sublingual preparations as an alternative (though evidence doesn't suggest superior absorption to oral tablets) For those on injections, checking the specific product's SmPC for excipient information In the UK, hydroxocobalamin injection is the licensed first-line treatment for B12 deficiency requiring parenteral therapy