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There are many potential processes underlying MTX toxicity (Reference Chan and Cronstein33) , but no effective treatments to ameliorate the condition exist

Analysis of global gene expression profile of rice in response to methylglyoxal indicates its possible role as a stress signal molecule

doi: 10.1161/ATVBAHA.107.159178 164

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Pulmonary fibrosis and oxidative stress model: NF-B / Nrf2 signaling pathway involvement: Redox Biology publication examining oxidative regulation mechanisms: These studies describe GHK-Cu interacting with redox-sensitive signaling networks and inflammatory mediators