In the United States, prescribing information for all medications licensed for obesity that act on the CNS, including the GLP-1RAs liraglutide 3 mg (Saxenda) and semaglutide 2.4 mg (Wegovy), must include the recommendation of monitoring for depression and suicidal ideation 231
Despite largely acceptable profiles, cautious investigation is necessary for long-term safety issues
If youre interested in this alternative to injectable GLP-1s, ask your provider or look for clinics that specialize in compounded or name-brand prescriptions
Glucagon-like peptide-1 receptor agonists: a new frontier in treating alcohol use disorder
Kessler documents his experience in the new book Diet, Drugs, and Dopamine: The New Science of Achieving a Healthy Weight
Not only can health changes enhance the effectiveness of medications, but it can also reduce the necessary dosage