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The weight loss achieved by CagriSema (-20.4% at 68 weeks) is comparable to that reported with the dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist tirzepatide (-20.9% with the 15-mg dose at 72 weeks in SURMOUNT-1) [14]

Food intake is thus modulated by complementary mechanisms so as to maintain energy and weight homeostasis

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The best human evidence for DSIP involves small studies in people with chronic insomnia

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Pair shots with proper nutrition by staying hydrated, prioritizing lean protein, reducing processed foods, and eating leafy greens to support the livers fat metabolism processes