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These positive effects on glucose homeostasis coupled with the achievement of weight loss manage to reduce hepatic inflammation and steatosis and to improve liver function tests

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More importantly, metformin, a commonly used antidiabetic drug, has also been shown to treat AIH by upregulating growth arrest and DNA-damage inducible 45 (Gadd45) expression and inhibiting JNK phosphorylation

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Understanding these limitations helps set realistic expectations and encourages more cautious decision-making, which ultimately reduces risk

Although psyllium appears promising in improving cardiovascular health, individual differences in response to dietary interventions need to be considered