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Inject slowly over 1015 seconds

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Indeed, in astrocytes, Linuron synergized with IL-1 and TNF to induce unfolded protein accumulation and boosted pro-inflammatory gene expression such as Nos2, IL6, CSF2, and CLl2 (Hedstrm et al., 2018)

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This localization theoretically reduces systemic side effects and cancer concerns compared to long-acting analogs, though local effects may still influence surrounding tissues