Your body is literally rewiring its incretin signaling, and that takes energy
Its principal physiological role is to transport long-chain fatty acids into the mitochondria the energy-producing structures within cells where they are broken down to generate energy
But as labs, symptoms, and dose changes accumulate, those methods fragment context and make clinic visits longer and more stressful
During weight loss, particularly if dietary protein intake is insufficient (generally aim for 1.0-1.2g/kg/day unless contraindicated), there is a risk of losing lean muscle mass alongside fat tissue
however, a small fraction of these lesions gains further mutations required for transformation into melanoma, estimated at 1:3000 to 1:10,000 lifetime transformation risk for any particular nevus 5
Bottom line: New GLP-1 medicines may be only a few years away, but in the meantime, proven options like Ozempic and Wegovy already offer major health benefits