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A 1 mL U-100 syringe is commonly marked up to 100 units, a 0.5 mL syringe up to 50 units, and a 0.3 mL syringe up to 30 units

It is characterised by insulin-dependent diabetes mellitus, optic nerve atrophy, diabetes insipidus, hearing loss and neurodegeneration

In addition, reliance on diagnostic coding may underestimate the true incidence of suicidal ideation, as sensitivity and specificity of such codes are uncertain

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This approach is particularly important because there is no established protocol for discontinuing GLP-1 therapy in the medical literature