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Clinical Outcomes of Semaglutide in Patients with MASH The phase 3 ESSENCE trial enrolled 800 patients with biopsy-confirmed MASH and fibrosis stage F2F3 and demonstrated that semaglutide 2.4 mg/week produced significant histological and metabolic benefits over 72 weeks

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It is suggested that iron plays an important role in inducing autophagic cell death after cerebral hemorrhage, and this effect may be one of the secondary injury mechanisms of the brain (He et al., 2007)