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The genetics and neuropathology of amyotrophic lateral sclerosis

Hepcidin binds to the iron transporter ferroportin-1, inducing its internalization and degradation, restricting iron efflux from hepatocytes and limiting intestinal iron absorption, thus playing a crucial role in maintaining iron homeostasis [87]

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Studieson mice have shown that treatment with CJC-1295 every 48-72 hours can lead to higher body weight and length compared to placebo-treated mice