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The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy

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The definitive K i values reported in this study are obtained from nonlinear regression analysis, where kinetic parameters are calculated using all substrate and inhibitor concentration data simultaneously

Genotyping Genomic DNA was isolated from blood samples (Puregene Systems, Gentra)

Cytosolic NADP+-dependent isocitrate dehydrogenase protects macrophages from LPS-induced nitric oxide and reactive oxygen species