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Afterward, active transporters within the hepatic sinusoid membrane of hepatocytes efficiently clear these BAs

[PubMed: 8786016] (Among 328 patients with diabetic peripheral neuropathy treated with ALA [100, 600, or 1200 mg] or placebo intravenously 4 to 5 days per week for 3 weeks, total neuropathy symptom scores improved by 43%, 63% and 58% with ALA vs 38% with placebo, while adverse events were similar with the lower doses as with placebo [14% and 18% vs 21%] but higher with the highest dose [33%]

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As stated by Gul [66], application of Zn resulted in the least amount of membrane damage and H 2 O 2 concentrations