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Supplementary Video 2 (download MP4 Close-up of the D1 active site bearing the R359K mutation from an MD simulation sampled immediately after in silico-transformation of ATP into ADP and P i for 2 s

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In the subsequent cycles, the study group showed significant improvements in in vivo oocyte maturation rate at retrieval (p=0.002), normal in vitro fertilization rate (p=0.003), blastocyst formation rate (p=0.003), and usable blastocyst rate compared to controls

Up-regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-cell Proliferation and Transforms T-cells Towards a Tumor-tolerating Phenotype