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Even a 10 % miscalculation during reconstitution means you either get too little active substance or unintentionally overdose

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Very common side effects (affecting more than 1 in 10 people) include nausea, diarrhoea, vomiting, constipation, and decreased appetite

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Paul and Brady also note that various single-nucleotide polymorphisms (SNPs) may influence the efficacy and bioavailability, but that at this time there is neither sufficient clinical research in this area nor are tests for these SNPs commercially available