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Consult a physician before use if you have a pre-existing medical condition.

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Most patients experience onset between days 3 and 21 after their first injection or oral dose, with the highest incidence occurring during the first dose escalation phase

The point estimate of the ratio (ESRD group/normal renal function group) for AUC 48 (without hemodialysis) was 0.72 (90% CI 0.570.91) and for AUC 4896 (with hemodialysis) was 0.82 (90% CI 0.670.99)

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