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For the right patient, gastric sleeve is not just one of many GLP-1 alternatives

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Importantly, as there has been discussion in the media about possible adverse effects of the drugs on mental health, the group taking the drug had a lower incidence of schizophrenia, alcohol and drug use disorders, and less suicidal ideation

PMID: 35985340.

The results demonstrated that the infusion of GLP-1 during high level of glycemia significantly protects endothelial dysfunction and decreases hyperglycemia-induced oxidative stress see Table 2

This cytoprotective effect is mediated by PI3K and partially dependent on ERK1/2 and seems to be glucose-independent