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The answer would be that GLP-1 receptor agonists mimic natural gut hormones

Some patients notice reduced appetite, while others feel little change at this starting dose, and scale movement is typically modest either way

goal 23 semisoft stools per day) plus albumin (1.5 g/kg/day) or lactulose alone, and treatment was continued until recovery of HE or for a maximum of 10 days

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The finding points to the drugs own target receptors, recasting uneven results and stomach side effects as part of the same biological story