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For instance, vitamin C (ascorbic acid) may interfere with copper binding

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"We emphasize that as the clinical investigator, it is your responsibility to ensure that studies are conducted in accordance with the investigational plan, both to protect the rights, safety, and welfare of subjects and to ensure the integrity of study data." FDA noted that two of the nine randomized subjects who received the investigational product were not eligible under the enrollment criteria

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This process facilitated the accumulation of nano-micelles in tumors, leading to glutathione (GSH) elimination and inhibition of energy metabolism

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