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Currently, several senolytics were reported to kill senescent cells ( In this study, we tested the hypothesis that FOXO4-DRI treatment can selectively remove senescent cells in expanded human chondrocytes, thus enhancing their potential to generate high-quality cartilage

Methods 81 , 127134 (2010)

Expanded major adverse cardiovascular events (MACE) were defined as a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal ischemic stroke, and hospitalization for heart failure

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Established cardiovascular disease: The proven cardiovascular protection makes GLP-1 medications first-choice treatment for patients with heart disease

After washing, the membranes were incubated with HRP-conjugated secondary IgG (1:2,000, Beyotime Biotechnology) for 1 h at room temperature