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44 Recent findings have shed light on how iron overload affects cardiac mitochondrial function, leading to reduced mitochondrial respiration, increased synthesis of ROS, mitochondrial membrane depolarization, and mitochondrial swelling, which affect the mitochondrial fission and fusion process

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5 Riboflavin in gene therapy and molecular targeting of neurological disorders With the advent of high-throughput sequencing and broader genetic testing, an increasing number of inherited neurometabolic disorders linked to riboflavin metabolism have been identified