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doi: 10.1016/j.molmet.2021.101407, 79

Common signs include dizziness, lightheadedness, fainting, fatigue, and weakness

It has been suggested that keratinocytes, through the release of biological mediators, proopiomelanocortin (POMC)-derived peptides, basic fibroblast growth factor, and endothelins, regulate proliferation and differentiation of melanocytes and stimulate melanogenesis through receptor-mediated signalling pathways [20]