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Contrarily, BPC 157 mice have much less pronounced edema (black arrow), weak cellular infiltrate, and exudate, and the blood vessels walls seem to be more preserved (dashed black arrow) and in more vessels, endothelial cell can be observed

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A randomized controlled trial (NCT04111775) demonstrated that oral charcoal adsorbent AST-120 reduces serum IS concentrations by 58% and decreases the urinary protein-to-creatinine ratio by 29% after 12 weeks, providing evidence that targeting gut-derived uremic toxins offers potential therapeutic benefits for established DN (28, 29)

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