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The medications address the biological drivers of obesity (hormonal signaling, appetite regulation) but do not permanently rewire these systems

A Therapeutic Use Exemption (TUE) would be required for legitimate medical use by an athlete, but it is very difficult to obtain for S2 substances

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ER and mitochondria specific lipids having at least a fold-change of 5 relative to the control-IP were selected

Nutrients, 13 (12)

As semaglutide suppresses appetite, some people unconsciously compensate by choosing calorie-dense foods for the smaller amounts they do eat