Direct Answer For gut-related targets, oral BPC-157 capsules have reasonable biological plausibility based on animal data showing local activity in gastric and intestinal tissue
It is a sequence of 15 amino acids that acts like a biological repair signal, telling injured tissue to do what healthy tissue already knows how to do: build blood vessels, lay down collagen, close wounds, and calm inflammation
The compound is rapidly reduced to leukomethylene blue in tissues, which is then excreted in urine, often causing a blue discoloration
doi: 10.1016/j.neuroscience.2008.04.001
Before adding any peptide to a lupus research protocol, its mechanism must be evaluated specifically for compatibility with autoimmune pathology
Epidemiology: High levels of vitamin B12 were found in: Causes: Excessive supplementation (a direct increase in plasma vitamin B12 by excess intake or administration) Increased release of vitamin B12 from tissue stores (liberation from an internal reservoir): Solid tumors (especially hepatic or hematologic malignancies) Liver metastases Increased binding proteins: 7 Excess production: Liver disease (e.g., hepatitis, cirrhosis, hepatocellular carcinoma) damaged hepatocytes release haptocorrin (transcobalamin I) and B12 into circulation Myeloproliferative disorders these increase granulocyte production, which leads to more haptocorrin (transcobalamin I/III), a B12-binding protein produced by proliferating myeloid cells