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GLP-1 receptor agonists: reminder of potential side effects and awareness of misuse

Ghrelin stimulates food intake by acting on hypothalamic neuropeptide Y (NPY)/ agouti/related peptide (AgRP) and proopiomelanocortin (POMC) neurons (Chen et al., 2004)

Introduction Eli Lillys recent announcement of successful Phase 3 trial results for orforglipron marks a significant milestone in metabolic disease treatment

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There are few studies on GLP-1RAs and colorectal tumors at home or abroad

Excessive generation of reactive oxygen species (ROS) has been identified as a major pathological driver, sustaining pro-inflammatory cascades and compromising fibroblast functionality, thereby underscoring the critical role of redox balance and antioxidant-based interventions in promoting regenerative healing