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Kristi Tough DeSapri, MD, founding physician at Bone and Body Womens Health, in Winnetka, Illinois, has noticed a marked uptick in her peri/menopausal patients asking about weight-loss drugsspecifically, glucagon-like peptide 1 (GLP-1) receptor antagonists, like Wegovy and Ozempic (a diabetes medicine linked with weight loss), among others

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Due to the unavailability of force-field libraries for complex chemical modifications (e.g., pegylation, penicillamine, etc.), the structures of the peptides containing such modifications were not predicted

For individuals with obesity or those at risk of developing type 2 diabetes, GLP-1 injections offer a proven option to help manage weight and improve overall health

They act within our body with actions that lead to better sugar metabolism, better eating hormone management, and noticeable weight loss