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Glucagon-like peptide-1 receptor (GLP-1R) agonists show efficacy in controlling blood glucose and serve as a treatment modality for diabetes mellitus

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Desai A, Yamazaki T, Dietz AJ, et al

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On July 10, 2024, Kuei-Pin Huang and colleagues published a paper in Nature titled Dissociable Hindbrain GLP1R Circuits for Satiety and Aversion. The study suggests that future weight loss medications could selectively target GLP1R neurons in the nucleus of the solitary tract (NTS) to avoid inducing aversion, thereby improving treatment adherence and effectiveness [1]