Metformin: from mechanisms of action to therapies
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Security: The incidence of gastrointestinal adverse events was 7.3% (nausea) and 6.3% (diarrhea) in the high-dose form, both of which were mild and no vomiting or severe diarrhea was reported
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The compound was first studied because researchers noticed the stomach has a remarkable ability to protect and repair its own lining, even sitting in a bath of acid that would burn most tissue