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In 1999 De Marzo et al proposed that proliferative inflammatory atrophy (PIA) is a precursor to PIN and cancer

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10.1126/science.2114039 142 ZenkeF.GerstnerW

[9] [10] Changes during ontogeny [edit] In the rat blood plasma, the GPx-3 activity is low during the first two weeks after birth and rapidly increasing during transition from milk nutrition to solid food

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