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Your doctor may also order an X-ray and biopsy of the bursa fluid to test for infection

Their headline weight-loss figures are similar (about 20.4% for CagriSema in REDEFINE 1 and about 20.9% for tirzepatide 15 mg in SURMOUNT-1), but those come from separate trials in different populations over different durations

The recommended starting point for finding UK trials is: NIHR Be Part of Research (bepartofresearch.nihr.ac.uk) the UK's public-facing portal for finding and joining clinical research studies ClinicalTrials.gov and the EU Clinical Trials Register international registries of ongoing studies, including the REDEFINE and TRIUMPH programmes Referral via a GP or specialist to a trial centre In the meantime, men with obesity or type 2 diabetes should be aware that NICE-approved treatments are already available and may offer meaningful clinical benefit: Semaglutide (Wegovy) is approved by NICE (TA875) for weight management in adults with a BMI 35 kg/m (or lower thresholds for certain ethnic groups) and at least one weight-related comorbidity, subject to specialist tier service criteria and duration requirements

Hence the skin looks a bit brighter

Data or Concepts to Include: FDA cosmetics are regulated differently from approved drugs

Secondly, there is a lack of standardized methods for assessing treatment effects (Table 4)