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While low concentrations of ROS have positive effects on cell signaling, proliferation, differentiation, and apoptosis, higher concentrations of ROS contribute to the pathophysiology of a number of chronic and degenerative diseases [40]

For instance, pregnant women with undiagnosed or untreated hypothyroidism have an increased risk of experiencing a miscarriage and preterm delivery

Hormone-linked redox status and its modulation by antioxidants

Mouse models are highly effective in age related studies as the shortened timeline allows observation of the full impact of treatments in months as opposed to the years of human clinical trials

While more research is needed on the impact of senolytics on diseases and disorders of aging, the researchers say the results of occasional dosing reduces risks from having to give drugs continuously

Gastrointestinal mucosal protection and inflammatory bowel research