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GLP-1RAs maintain vascular health GLP-1 plays crucial role in proper functioning of vascular endothelium, and is linked to improved endothelial function, and enhanced nitric oxide synthase-driven vasodilation [22]
Robust clinical trial data demonstrate that GLP-1 receptor agonists produce favorable effects on lipid profiles that may include mechanisms beyond those attributable to weight loss alone
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The difference is that retatrutide adds a third, GIP, a second incretin hormone that may improve how the body handles fat and can ease nausea compared with GLP-1 alone
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