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Another significant benefit of L-Carnitine is its role in cardiovascular health

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The high HCC incidence rate in GAN DIO-NASH-HCC mice is comparable to other Western diet-based mouse models of NASH 46,62,63,64 , also demonstrating similar HCC molecular subclass-specificity 60,62,63

Those are different conditions with different treatments, which is why the article draws that line at six months

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Orlistat increases urinary oxalate excretion, raising the risk of calcium oxalate kidney stones and, rarely, oxalate nephropathy it should be used with caution or avoided in people with CKD or a history of kidney stones