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FPN activity is controlled by another protein produced in the liver called hepcidin, which reduces iron translocation by degrading FPN in the basement membranes of duodenocytes, macrophages, and hepatocytes, thereby lowering serum iron levels [18]

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Psilopanagioti A., Nikou S., Logotheti S., Arbi M., Chartoumpekis D.V., Papadaki H

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Sodium glucose cotransporter-2 inhibition in heart failure: potential mechanisms, clinical applications, and summary of clinical trials