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+ - Early Effects: Many patients notice initial changes-such as increased energy levels or a decrease in appetite-within the first 12 weeks of consistent use

Moreover IR in PCOS was shown to destroy the effect of gonadotropins, enhance the sensitivity of follicular membrane cells to the luteinizing hormone, and increase the expression of P450c17 and 3-hydroxysteroid dehydrogenase type 2, leading to increased production of androgen (152)

This initial period allows the body to adjust to the medication, minimizing gastrointestinal side effects

While panic attacks are not a standard side effect, some people may experience physical symptoms like a racing heart or nausea that can trigger a panic response

Semaglutide has a half-life of about 7 days

2007 Jun;47(3):216-21 (Ver) Wright C, Milne S, Leeson H