Wasting 30 mg of a 60 mg vial because it expired before you could use it is worse than buying two 15 mg vials and using them completely
The risk of worsening heart failure events alone dropped by 46% (HR 0.54)
Their effect lasts only while the medication is taken, and stopping it often leads to weight regain
The benefits for many outweigh the risks, especially when those risks are understood and managed
Cost differences matter too
Conversely, individuals with obesity show increased oxygen consumption in the insula, operculum, bilateral precuneus, and posterior cingulate cortex, along with the ventral putamen and Rolandic operculum, but decreased oxygen uptake in the lower caudatepatterns associated with increased impulsivity towards food stimuli (128130)