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(2006) investigated afamelanotide in a clinical study and observed increased melanin density and skin darkening, with enhanced photoprotection against UV-induced erythema [3]

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In clinic, this generally translates into restoring midface support just in front of and over the zygoma (cheekbone), softening deep nasolabial folds via indirect lift rather than simply chasing the line and refining the chin and jawline to replace lost volume from these key points of age related volume change