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Practical implementation involves decisions about administration, sourcing, monitoring, and professional guidance that determine whether a research protocol produces useful data or wasted time and money

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The programme included advice from a nutritionist on healthy eating, increasing exercise and overcoming the psychological barriers to weight loss, access to doctors, nurses and psychologists through the app and a course of the weight loss drug semaglutide (Ozempic or Wegovy)

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doi: 10.1016/j.bbrc.2025.151547 59