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We next exchanged the PPAR/ co-agonist Tesa with Lani, a PPAR// triple agonist that has previously been shown to ameliorate HFD-induced body weight gain 33,34 (Extended Data Fig

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A newer peptide, Retatrutide , is a triple receptor agonist in development

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Existing research provides important information, but it does not answer every long-term question