GOT1 knockout combined with cysteine depletion by erastin or IKE showed potent antitumor effects against these cells by reducing GSH and increasing ferroptosis 66
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No new data were generated or analyzed in this study
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Sources NIH Office of Dietary Supplements, Vitamin B12 Fact Sheet NIH Office of Dietary Supplements, Choline Fact Sheet MedlinePlus, Cyanocobalamin Injection Mayo Clinic, Vitamin B12 Injections and Weight Loss NCBI Bookshelf, Essential Amino Acids PubMed, Inositol Phosphate Signaling Network The American Journal of Clinical Nutrition, Lipotropic Agents and Lipid Transport