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A 2006 review of the field by an active research group described DSIP as a still unresolved riddle a description that, twenty years later, the published literature has not displaced (Kovalzon & Strekalova, 2006)

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To investigate the role of the integrin-FAK pathway in 25HC-mediated activation of a proinflammatory response in a pathophysiological setting, mimicking IAV infection, we administered 25HC to the mouse airway either in the presence or absence of a 1 integrin blocking antibody, previously employed to inhibit integrin activation in the mouse airway 45 , or the FAK inhibitor (PND-1186), which has been used in mice to block FAK activation 46

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