When to see a doctor Seek medical evaluation if: Hair loss persists beyond 9 to 12 months after weight stabilization You notice patchy bald spots rather than diffuse thinning Hair loss is accompanied by scalp pain, itching, or redness You have additional symptoms suggesting thyroid or nutritional issues The severity is extreme, with visible scalp showing through Hair loss began before starting tirzepatide or weight loss A dermatologist can perform a pull test, examine the scalp with dermoscopy, and order targeted blood work to distinguish telogen effluvium from other causes
GLP-1 RAs are currently being investigated for various new areas, such as cardiovascular diseases, non-alcoholic steatohepatitis (NASH), Alzheimers disease, and chronic kidney disease
However, compounded drugs are not FDA-approved
Together, these findings necessitate further investigations to ascertain whether coordinated inhibition of NMDA receptors in GLP-1 receptor neurons modulates neuronal activity beyond canonical feeding regions, such as the mesolimbic dopaminergic reward pathway
The adherence assumption: Pills don't automatically win The pharmaceutical industry assumes pills will automatically improve adherence over injections
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