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Recently, beetroot juice or concentrates have been linked to improved endothelial function, reduced blood pressure (BP), and enhanced exercise tolerance, all of which are effects implicated in the enterosalivary nitrate-nitrite-nitric oxide (NO) pathway, which augments vasodilation and tissue oxygen delivery

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However, when the energy charge is low, pyruvate is preferentially oxidized to CO 2 and H 2 O through the activities of the pyruvate dehydrogenase complex (PDHc) and the enzymes of the TCA cycle, with generation of approximately 15 moles of ATP per mole of pyruvate

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