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GLP-1 receptor agonists (like semaglutide and liraglutide) mimic this signal pharmacologically

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Gut Microbes The impact of very-low-calorie ketogenic diets on gut microbiota in individuals with obesity: a systematic review and meta-analysis The impact of very-low-calorie ketogenic diets on gut microbiota in individuals with obesity: a systematic re cited 2026 Feb 12];17:2566305

Newer dual and triple agonists in development, such as mazdutide , are expected to share the favorable UTI profile of the GLP-1 class given their similar mechanisms