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However, increased growth hormone activity may carry risks such as: insulin resistance fluid retention and joint swelling cardiovascular complications abnormal tissue growth Human orthopaedic evidence remains limited, and most musculoskeletal data are still preclinical
The fine gauge minimizes the puncture hole in the rubber stopper (extending the useful life of the vial) and creates less tissue trauma during subcutaneous administration
Some may experience minor side effects such as: Redness or swelling at the injection site Temporary soreness or bruising Less commonly, side effects could include: Mild headaches Nausea Itchy skin or rash Should you notice any prolonged side effects, we recommend speaking with your GP or calling NHS 111 for advice
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Although treatment with PN may provide partial response, 75% of patients still exhibit residual developmental delays and mental retardation [25]
