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That it needs a comprehensive care program, not just a prescription, but nutrition, physical activity, testing for comorbidities. Its GPs who will be at the centre of this, and those who can support GPs through well-oiled health expertise. Becca Whitehead is a freelance journalist and health writer

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For a detailed clinical comparison of mechanisms, weight loss outcomes, and FDA status, see the retatrutide vs tirzepatide comparison guide

If GLP-1 drugs are the best choice for you, it will depend on your healthcare objectives and personal circumstances

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